BDBM50092268 5-(4-nitrobenzylidene)-2-thioxothiazolidin-4-one::5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::CHEMBL66064

SMILES: [O-][N+](=O)c1ccc(C=C2SC(S)=NC2=O)cc1

InChI Key: InChIKey=FRWNAQDBODEVAL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50092268 (5-(4-nitrobenzylidene)-2-thioxothiazolidin-4-one |...) Show SMILES [O-][N+](=O)c1ccc(C=C2SC(S)=NC2=O)cc1 |w:7.6,c:11| Show InChI InChI=1S/C10H6N2O3S2/c13-9-8(17-10(16)11-9)5-6-1-3-7(4-2-6)12(14)15/h1-5H,(H,11,13,16)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5b RNA polymerase				J Med Chem 49: 1034-46 (2006) Article DOI: 10.1021/jm050859x BindingDB Entry DOI: 10.7270/Q2CJ8D3W
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Enterobacter cloacae)	BDBM50092268 (5-(4-nitrobenzylidene)-2-thioxothiazolidin-4-one |...) Show SMILES [O-][N+](=O)c1ccc(C=C2SC(S)=NC2=O)cc1 |w:7.6,c:11| Show InChI InChI=1S/C10H6N2O3S2/c13-9-8(17-10(16)11-9)5-6-1-3-7(4-2-6)12(14)15/h1-5H,(H,11,13,16)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against class A Beta-lactamase TEM isolated from Enterobacter coli				Bioorg Med Chem Lett 10: 2179-82 (2001) BindingDB Entry DOI: 10.7270/Q2T15456
					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50092268 (5-(4-nitrobenzylidene)-2-thioxothiazolidin-4-one |...) Show SMILES [O-][N+](=O)c1ccc(C=C2SC(S)=NC2=O)cc1 |w:7.6,c:11| Show InChI InChI=1S/C10H6N2O3S2/c13-9-8(17-10(16)11-9)5-6-1-3-7(4-2-6)12(14)15/h1-5H,(H,11,13,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against class C Beta-lactamase isolated from Enterobacter cloacae				Bioorg Med Chem Lett 10: 2179-82 (2001) BindingDB Entry DOI: 10.7270/Q2T15456
					More data for this Ligand-Target Pair