BindingDB PrimarySearch

BDBM50092310 CHEMBL3581661::US9675697, Cpd. No. 23

SMILES: COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)[nH]nc3C3CC3)c21

InChI Key: InChIKey=WHDUHJYPRJXLGF-UHFFFAOYSA-N

Data: 12 KI 2 IC50 21 Kd

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50092310
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	3.20	-11.6	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	7.30	-11.1	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD2 BD1 (72 to 205 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	11	-10.8	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	12	-10.8	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	12	-10.8	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD2 BD2 (349 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	25	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription intermediary factor 1-alpha (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated TRIM24 (790 to 972 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometry...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated ATAD2A (981 to 1108 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Myeloid/lymphoid or mixed-lineage leukemia (MLL) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated MLL1 (1566 to 1784 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry met...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated TAF1B2 (155 to 276 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry met...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRG1 (59 to 180 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry method				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Protein polybromo-1 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated PB1BR5 (645 to 766 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry met...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD2 BD1 (72 to 205 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated CREBBP (1043 to 1159 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	26	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	20	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	18	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	21	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	29	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2) (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	13	n/a	n/a	n/a	7.4	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...				US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRD2 BD2 (349 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2B (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated ATAD2B (953 to 1086 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2B (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BAZ2B (2054 to 2168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair