BDBM50092421 1-(2,6-Dichloro-phenyl)-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-imidazolidin-2-one::CHEMBL121497

SMILES: Clc1cccc(Cl)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O

InChI Key: InChIKey=ZJFDCQNJERMIKE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092421 (1-(2,6-Dichloro-phenyl)-3-{2-[1-(2,3-dihydro-benzo...) Show SMILES Clc1cccc(Cl)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O Show InChI InChI=1S/C25H29Cl2N3O3/c26-20-4-3-5-21(27)24(20)30-15-14-29(25(30)31)13-10-18-8-11-28(12-9-18)16-19-17-32-22-6-1-2-7-23(22)33-19/h1-7,18-19H,8-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.				J Med Chem 43: 3653-64 (2000) BindingDB Entry DOI: 10.7270/Q2MW2GD3
					More data for this Ligand-Target Pair