BDBM50092443 3-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-1-methyl-1-phenyl-urea::CHEMBL120812

SMILES: CN(C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1

InChI Key: InChIKey=ZWFOVLJNNFKCBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092443 (3-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-...) Show SMILES CN(C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 Show InChI InChI=1S/C24H31N3O3/c1-26(20-7-3-2-4-8-20)24(28)25-14-11-19-12-15-27(16-13-19)17-21-18-29-22-9-5-6-10-23(22)30-21/h2-10,19,21H,11-18H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.				J Med Chem 43: 3653-64 (2000) BindingDB Entry DOI: 10.7270/Q2MW2GD3
					More data for this Ligand-Target Pair