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BDBM50092446 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(4-hydroxy-phenyl)-urea::CHEMBL122821

SMILES: Oc1ccc(NC(=O)NCCC2CCN(CC3COc4ccccc4O3)CC2)cc1

InChI Key: InChIKey=YYCJXQMVIXDIPD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092446   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50092446
PNG
(1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-...)
Show SMILES Oc1ccc(NC(=O)NCCC2CCN(CC3COc4ccccc4O3)CC2)cc1
Show InChI InChI=1S/C23H29N3O4/c27-19-7-5-18(6-8-19)25-23(28)24-12-9-17-10-13-26(14-11-17)15-20-16-29-21-3-1-2-4-22(21)30-20/h1-8,17,20,27H,9-16H2,(H2,24,25,28)
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PC sid
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Similars
PubMed
n/an/a 15n/an/an/an/an/an/a



Centre de Recherche Pierre Fabre

Curated by ChEMBL


Assay Description
In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.

J Med Chem 43: 3653-64 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GD3
More data for this
Ligand-Target Pair