BDBM50092561 4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl ester::CHEMBL127876

SMILES: COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1cccc(Cl)c1

InChI Key: InChIKey=MHQQEYDQTYTXSS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50092561 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-ch...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H23Cl2N3O3/c1-27-19-13-18(23)17(22)12-16(19)20(26)28-10-9-24-5-7-25(8-6-24)15-4-2-3-14(21)11-15/h2-4,11-13H,5-10,23H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]-GR-113,...				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair