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SMILES: Ic1cccc(c1)-c1cc(cc2cccnc12)C(=O)c1ccccc1

InChI Key: InChIKey=GLMLPGHDUUQGGA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092629   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))		BDBM50092629
PNG
(CHEMBL123576 | [8-(3-Iodo-phenyl)-quinolin-6-yl]-p...)
Show SMILES Ic1cccc(c1)-c1cc(cc2cccnc12)C(=O)c1ccccc1
Show InChI InChI=1S/C22H14INO/c23-19-10-4-8-16(13-19)20-14-18(12-17-9-5-11-24-21(17)20)22(25)15-6-2-1-3-7-15/h1-14H
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem
PubMed
n/an/a 15n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PDE4A expressed in Sf9 cells

J Med Chem 43: 3820-3 (2000)


BindingDB Entry DOI: 10.7270/Q23T9GG9
More data for this
Ligand-Target Pair