null

SMILES: CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=WGQLQLVNMRNWRA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50092684 (4-[(4-Chloro-phenyl)-piperazin-1-yl-methyl]-N,N-di...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H28ClN3O/c1-3-25(4-2)22(27)19-7-5-17(6-8-19)21(26-15-13-24-14-16-26)18-9-11-20(23)12-10-18/h5-12,21,24H,3-4,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligand				J Med Chem 43: 3878-94 (2000) BindingDB Entry DOI: 10.7270/Q2QN661W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50092684 (4-[(4-Chloro-phenyl)-piperazin-1-yl-methyl]-N,N-di...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H28ClN3O/c1-3-25(4-2)22(27)19-7-5-17(6-8-19)21(26-15-13-24-14-16-26)18-9-11-20(23)12-10-18/h5-12,21,24H,3-4,13-16H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity against cloned human Opioid receptor mu 1 using [125I]FK33824 as radioligand				J Med Chem 43: 3878-94 (2000) BindingDB Entry DOI: 10.7270/Q2QN661W
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50092684 (4-[(4-Chloro-phenyl)-piperazin-1-yl-methyl]-N,N-di...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H28ClN3O/c1-3-25(4-2)22(27)19-7-5-17(6-8-19)21(26-15-13-24-14-16-26)18-9-11-20(23)12-10-18/h5-12,21,24H,3-4,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity against cloned human Opioid receptor kappa 1 using [125I]-D-Pro10-dynorphin A[1-11] as radioligand				J Med Chem 43: 3878-94 (2000) BindingDB Entry DOI: 10.7270/Q2QN661W
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50092684 (4-[(4-Chloro-phenyl)-piperazin-1-yl-methyl]-N,N-di...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H28ClN3O/c1-3-25(4-2)22(27)19-7-5-17(6-8-19)21(26-15-13-24-14-16-26)18-9-11-20(23)12-10-18/h5-12,21,24H,3-4,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Agonist potency was measured using GTP gamma-[35S] binding assay				J Med Chem 43: 3878-94 (2000) BindingDB Entry DOI: 10.7270/Q2QN661W
					More data for this Ligand-Target Pair