BDBM50092699 CHEMBL126842::N,N-Diethyl-4-[(1-methyl-piperidin-4-ylidene)-phenyl-methyl]-benzamide

SMILES: [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)\c1ccccc1

InChI Key: InChIKey=ZREUYGHIRGMBCR-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50092699 (CHEMBL126842 | N,N-Diethyl-4-[(1-methyl-piperidin-...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)\c1ccccc1 Show InChI InChI=1S/C24H30N2O/c1-4-26(5-2)24(27)22-13-11-20(12-14-22)23(19-9-7-6-8-10-19)21-15-17-25(3)18-16-21/h6-14H,4-5,15-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity on cloned opioid receptor delta 1 in human HEK293S cells using [125I]-[D-Ala2]-deltorphin II as radioligand.				J Med Chem 43: 3895-905 (2000) BindingDB Entry DOI: 10.7270/Q2KW5F95
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50092699 (CHEMBL126842 | N,N-Diethyl-4-[(1-methyl-piperidin-...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)\c1ccccc1 Show InChI InChI=1S/C24H30N2O/c1-4-26(5-2)24(27)22-13-11-20(12-14-22)23(19-9-7-6-8-10-19)21-15-17-25(3)18-16-21/h6-14H,4-5,15-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity on cloned opioid receptor kappa 1 in human HEK293S cells using [125I]-D-Pro10-dynorphin A[1-11] as radioligand.				J Med Chem 43: 3895-905 (2000) BindingDB Entry DOI: 10.7270/Q2KW5F95
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50092699 (CHEMBL126842 | N,N-Diethyl-4-[(1-methyl-piperidin-...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)\c1ccccc1 Show InChI InChI=1S/C24H30N2O/c1-4-26(5-2)24(27)22-13-11-20(12-14-22)23(19-9-7-6-8-10-19)21-15-17-25(3)18-16-21/h6-14H,4-5,15-18H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Binding affinity on cloned opioid receptor mu 1 in human HEK293S cells using [125I]FK33824 as radioligand.				J Med Chem 43: 3895-905 (2000) BindingDB Entry DOI: 10.7270/Q2KW5F95
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50092699 (CHEMBL126842 | N,N-Diethyl-4-[(1-methyl-piperidin-...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)\c1ccccc1 Show InChI InChI=1S/C24H30N2O/c1-4-26(5-2)24(27)22-13-11-20(12-14-22)23(19-9-7-6-8-10-19)21-15-17-25(3)18-16-21/h6-14H,4-5,15-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	161	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Effective concentration as delta agonist potency using [35S]GTP-gamma-S binding assay.				J Med Chem 43: 3895-905 (2000) BindingDB Entry DOI: 10.7270/Q2KW5F95
					More data for this Ligand-Target Pair