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BDBM50092753 (Racemate)-1-Phenyl-4-(2-phenyl-cyclopropylmethyl)-piperazine::CHEMBL341497

SMILES: C([C@H]1C[C@@H]1c1ccccc1)N1CCN(CC1)c1ccccc1

InChI Key: InChIKey=DDRAKDPEZWFDFW-UYAOXDASSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092753   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))
BDBM50092753
PNG
((Racemate)-1-Phenyl-4-(2-phenyl-cyclopropylmethyl)...)
Show SMILES C([C@H]1C[C@@H]1c1ccccc1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H24N2/c1-3-7-17(8-4-1)20-15-18(20)16-21-11-13-22(14-12-21)19-9-5-2-6-10-19/h1-10,18,20H,11-16H2/t18-,20-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 48n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Binding affinity to dopamine receptor D4 cloned from human, using [3H]- YM09151 as competitive ligand


J Med Chem 43: 3923-32 (2000)


BindingDB Entry DOI: 10.7270/Q2HM595B
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50092753
PNG
((Racemate)-1-Phenyl-4-(2-phenyl-cyclopropylmethyl)...)
Show SMILES C([C@H]1C[C@@H]1c1ccccc1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H24N2/c1-3-7-17(8-4-1)20-15-18(20)16-21-11-13-22(14-12-21)19-9-5-2-6-10-19/h1-10,18,20H,11-16H2/t18-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 37n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Binding affinity to dopamine receptor D2 cloned from human, using [3H]- YM09151 as competitive ligand


J Med Chem 43: 3923-32 (2000)


BindingDB Entry DOI: 10.7270/Q2HM595B
More data for this
Ligand-Target Pair