BDBM50092835 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-3,3-dimethyl-butan-1-one; compound with but-2-enedioic acid::CHEMBL128357

SMILES: CC(C)(C)CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=OCAFUUZMEJOXBW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50092835 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-3,3-di...) Show SMILES CC(C)(C)CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C18H24N2O2/c1-18(2,3)11-17(21)14-6-8-16(9-7-14)22-10-4-5-15-12-19-13-20-15/h6-9,12-13H,4-5,10-11H2,1-3H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine				J Med Chem 43: 3987-94 (2000) BindingDB Entry DOI: 10.7270/Q2833SRN
					More data for this Ligand-Target Pair