BDBM50092839 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2,6-dimethyl-phenyl}-ethanone; compound with but-2-enedioic acid(0.5M H2O)::CHEMBL128057

SMILES: CC(=O)c1c(C)cc(OCCCc2cnc[nH]2)cc1C

InChI Key: InChIKey=LGLQFQUUMYVWJG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50092839 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2,6-dimethyl-p...) Show SMILES CC(=O)c1c(C)cc(OCCCc2cnc[nH]2)cc1C Show InChI InChI=1S/C16H20N2O2/c1-11-7-15(8-12(2)16(11)13(3)19)20-6-4-5-14-9-17-10-18-14/h7-10H,4-6H2,1-3H3,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine				J Med Chem 43: 3987-94 (2000) BindingDB Entry DOI: 10.7270/Q2833SRN
					More data for this Ligand-Target Pair