BDBM50092841 CHEMBL128690::Cyclobutyl-{4-[3-(1H-imidazol-4-yl)-propoxy]-phenyl}-methanone; compound with but-2-enedioic acid(0.25M H2O)
SMILES: O=C(C1CCC1)c1ccc(OCCCc2cnc[nH]2)cc1
InChI Key: InChIKey=OUTXXYFWOBIOOE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50092841 (CHEMBL128690 | Cyclobutyl-{4-[3-(1H-imidazol-4-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine | J Med Chem 43: 3987-94 (2000) BindingDB Entry DOI: 10.7270/Q2833SRN | |||||||||||
More data for this Ligand-Target Pair |