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SMILES: CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1C(F)(F)F

InChI Key: InChIKey=HCXMIUFXRDBPKU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092849   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50092849
PNG
(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-trifluoromet...)
Show SMILES CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O2/c1-10(21)13-5-4-12(7-14(13)15(16,17)18)22-6-2-3-11-8-19-9-20-11/h4-5,7-9H,2-3,6H2,1H3,(H,19,20)
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PC cid
PC sid
UniChem
PubMed
 17n/an/an/an/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine

J Med Chem 43: 3987-94 (2000)


BindingDB Entry DOI: 10.7270/Q2833SRN
More data for this
Ligand-Target Pair