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BDBM50092850 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-2-methyl-propan-1-one; compound with but-2-enedioic acid(0.5M H2O)::CHEMBL131021

SMILES: CC(C)C(=O)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=SDYUXFYMIDJMSZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50092850
PNG
(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-2-meth...)
Show SMILES CC(C)C(=O)c1ccc(OCCCc2cnc[nH]2)cc1
Show InChI InChI=1S/C16H20N2O2/c1-12(2)16(19)13-5-7-15(8-6-13)20-9-3-4-14-10-17-11-18-14/h5-8,10-12H,3-4,9H2,1-2H3,(H,17,18)
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Similars
PubMed
 4.80n/an/an/an/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine

J Med Chem 43: 3987-94 (2000)


BindingDB Entry DOI: 10.7270/Q2833SRN
More data for this
Ligand-Target Pair