BDBM50092851 5-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-5-oxo-pentanoic acid ethyl ester(H2O)::CHEMBL128926

SMILES: CCOC(=O)CCCC(=O)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=QTQYOLQBHRSCFW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50092851 (5-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-5-oxo-...) Show SMILES CCOC(=O)CCCC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C19H24N2O4/c1-2-24-19(23)7-3-6-18(22)15-8-10-17(11-9-15)25-12-4-5-16-13-20-14-21-16/h8-11,13-14H,2-7,12H2,1H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine				J Med Chem 43: 3987-94 (2000) BindingDB Entry DOI: 10.7270/Q2833SRN
					More data for this Ligand-Target Pair