BDBM50092854 4-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-but-3-en-2-one; compound with but-2-enedioic acid(0.5M H2O)::CHEMBL129607

SMILES: CC(=O)C=Cc1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=PMGWKOPQHJHIBT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50092854 (4-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-but-3-...) Show SMILES CC(=O)C=Cc1ccc(OCCCc2cnc[nH]2)cc1 |w:3.2| Show InChI InChI=1S/C16H18N2O2/c1-13(19)4-5-14-6-8-16(9-7-14)20-10-2-3-15-11-17-12-18-15/h4-9,11-12H,2-3,10H2,1H3,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine				J Med Chem 43: 3987-94 (2000) BindingDB Entry DOI: 10.7270/Q2833SRN
					More data for this Ligand-Target Pair