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BDBM50092862 5-[3-(1H-Imidazol-4-yl)-propoxy]-indan-1-one; compound with but-2-enedioic acid(H2O)::CHEMBL130952

SMILES: O=C1CCc2cc(OCCCc3cnc[nH]3)ccc12

InChI Key: InChIKey=HUQNCTURGOMYGP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092862   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50092862
PNG
(5-[3-(1H-Imidazol-4-yl)-propoxy]-indan-1-one; comp...)
Show SMILES O=C1CCc2cc(OCCCc3cnc[nH]3)ccc12
Show InChI InChI=1S/C15H16N2O2/c18-15-6-3-11-8-13(4-5-14(11)15)19-7-1-2-12-9-16-10-17-12/h4-5,8-10H,1-3,6-7H2,(H,16,17)
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PubMed
 17n/an/an/an/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Compounds were tested for their effect at histamine H3 receptors in vitro on synaptosomes of rat cerebral cortex for the release of [3H]histamine

J Med Chem 43: 3987-94 (2000)


BindingDB Entry DOI: 10.7270/Q2833SRN
More data for this
Ligand-Target Pair