BDBM50093045 CHEMBL76466::{2-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine

SMILES: COc1ccc(cc1)S(=O)(=O)n1cc(CCN(C)C)c2cc(OC)ccc12

InChI Key: InChIKey=OJPTTYMYFMZMRB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50093045 (CHEMBL76466 | {2-[5-Methoxy-1-(4-methoxy-benzenesu...) Show SMILES COc1ccc(cc1)S(=O)(=O)n1cc(CCN(C)C)c2cc(OC)ccc12 Show InChI InChI=1S/C20H24N2O4S/c1-21(2)12-11-15-14-22(20-10-7-17(26-4)13-19(15)20)27(23,24)18-8-5-16(25-3)6-9-18/h5-10,13-14H,11-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...				Bioorg Med Chem Lett 10: 2295-9 (2001) BindingDB Entry DOI: 10.7270/Q29C6WP6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50093045 (CHEMBL76466 | {2-[5-Methoxy-1-(4-methoxy-benzenesu...) Show SMILES COc1ccc(cc1)S(=O)(=O)n1cc(CCN(C)C)c2cc(OC)ccc12 Show InChI InChI=1S/C20H24N2O4S/c1-21(2)12-11-15-14-22(20-10-7-17(26-4)13-19(15)20)27(23,24)18-8-5-16(25-3)6-9-18/h5-10,13-14H,11-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.				J Med Chem 44: 3881-95 (2001) BindingDB Entry DOI: 10.7270/Q2T72GRW
					More data for this Ligand-Target Pair