BDBM50093046 CHEMBL75734::{2-[1-(2,5-Dimethoxy-benzenesulfonyl)-5-methoxy-1H-indol-3-yl]-ethyl}-dimethyl-amine
SMILES: COc1ccc(OC)c(c1)S(=O)(=O)n1cc(CCN(C)C)c2cc(OC)ccc12
InChI Key: InChIKey=GPIKYOXOHSCLOQ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50093046 (CHEMBL75734 | {2-[1-(2,5-Dimethoxy-benzenesulfonyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die... | Bioorg Med Chem Lett 10: 2295-9 (2001) BindingDB Entry DOI: 10.7270/Q29C6WP6 | |||||||||||
More data for this Ligand-Target Pair |