BDBM50093047 CHEMBL75758::{2-[1-(2,5-Dimethoxy-benzenesulfonyl)-4-methoxy-1H-indol-3-yl]-ethyl}-dimethyl-amine

SMILES: COc1ccc(OC)c(c1)S(=O)(=O)n1cc(CCN(C)C)c2c(OC)cccc12

InChI Key: InChIKey=HAPPPGGEJSADKP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50093047 (CHEMBL75758 | {2-[1-(2,5-Dimethoxy-benzenesulfonyl...) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)n1cc(CCN(C)C)c2c(OC)cccc12 Show InChI InChI=1S/C21H26N2O5S/c1-22(2)12-11-15-14-23(17-7-6-8-19(28-5)21(15)17)29(24,25)20-13-16(26-3)9-10-18(20)27-4/h6-10,13-14H,11-12H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...				Bioorg Med Chem Lett 10: 2295-9 (2001) BindingDB Entry DOI: 10.7270/Q29C6WP6
					More data for this Ligand-Target Pair