BDBM50093304 2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1-yl)-pentyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL423149

SMILES: CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccccc1Cl

InChI Key: InChIKey=LUSCJUZTUPFLPT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin-1 (Homo sapiens (Human))	BDBM50093304 (2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...) Show SMILES CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccccc1Cl Show InChI InChI=1S/C26H33ClN2O2/c1-19-11-10-12-20(2)28(19)17-8-3-9-18-29-23-15-6-7-16-24(23)31-25(26(29)30)21-13-4-5-14-22(21)27/h4-7,13-16,19-20,25H,3,8-12,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory activity against trypsin				J Med Chem 43: 4063-70 (2000) BindingDB Entry DOI: 10.7270/Q2W66K1H
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50093304 (2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...) Show SMILES CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccccc1Cl Show InChI InChI=1S/C26H33ClN2O2/c1-19-11-10-12-20(2)28(19)17-8-3-9-18-29-23-15-6-7-16-24(23)31-25(26(29)30)21-13-4-5-14-22(21)27/h4-7,13-16,19-20,25H,3,8-12,17-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of thrombin				J Med Chem 43: 4063-70 (2000) BindingDB Entry DOI: 10.7270/Q2W66K1H
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50093304 (2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...) Show SMILES CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccccc1Cl Show InChI InChI=1S/C26H33ClN2O2/c1-19-11-10-12-20(2)28(19)17-8-3-9-18-29-23-15-6-7-16-24(23)31-25(26(29)30)21-13-4-5-14-22(21)27/h4-7,13-16,19-20,25H,3,8-12,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor Xa.				J Med Chem 43: 4063-70 (2000) BindingDB Entry DOI: 10.7270/Q2W66K1H
					More data for this Ligand-Target Pair