BDBM50093753 (2S,3S)-2-Amino-3-benzyloxy-succinic acid::(2S,3S)-2-amino-3-(benzyloxy)succinic acid::(3S)-3-(BENZYLOXY)-L-ASPARTIC ACID::CHEMBL79140::DL-TBOA
SMILES: N[C@@H]([C@H](OCc1ccccc1)C(O)=O)C(O)=O
InChI Key: InChIKey=BYOBCYXURWDEDS-IUCAKERBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GRIA3 (RAT) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Institute for Bioorganic Research Curated by PDSP Ki Database | Mol Pharmacol 53: 195-201 (1998) Article DOI: 10.1124/mol.53.2.195 BindingDB Entry DOI: 10.7270/Q2RF5SJH | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Institute for Bioorganic Research Curated by PDSP Ki Database | Mol Pharmacol 53: 195-201 (1998) Article DOI: 10.1124/mol.53.2.195 BindingDB Entry DOI: 10.7270/Q2RF5SJH | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Institute for Bioorganic Research Curated by PDSP Ki Database | Mol Pharmacol 53: 195-201 (1998) Article DOI: 10.1124/mol.53.2.195 BindingDB Entry DOI: 10.7270/Q2RF5SJH | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 8.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.61E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.37E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of [14C]glutamate uptake at human EAAT3 expressed in african green monkey COS1 cells | Bioorg Med Chem 16: 7740-8 (2008) Article DOI: 10.1016/j.bmc.2008.07.001 BindingDB Entry DOI: 10.7270/Q2TM79XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 955 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method | J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 4 (Rattus norvegicus) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 4 (Rattus norvegicus) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Berne Curated by ChEMBL | Assay Description Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | J Med Chem 53: 7236-50 (2010) Article DOI: 10.1021/jm100959g BindingDB Entry DOI: 10.7270/Q27081NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Berne Curated by ChEMBL | Assay Description Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | J Med Chem 53: 7236-50 (2010) Article DOI: 10.1021/jm100959g BindingDB Entry DOI: 10.7270/Q27081NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50093753 ((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | Bioorg Med Chem Lett 10: 2407-10 (2001) Checked by Author BindingDB Entry DOI: 10.7270/Q2CR5TVN | |||||||||||
More data for this Ligand-Target Pair |