BDBM50093924 2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-pyrimidin-5-ylmethyl-1-thiophen-2-ylmethyl-1H-pyrimidin-4-one::CHEMBL85805

SMILES: Clc1ccc(cc1)C(=O)CCCCCCCSc1nc(=O)c(Cc2cncnc2)cn1Cc1cccs1

InChI Key: InChIKey=JXOWPNYSPLGKNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093924 (2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-pyri...) Show SMILES Clc1ccc(cc1)C(=O)CCCCCCCSc1nc(=O)c(Cc2cncnc2)cn1Cc1cccs1 Show InChI InChI=1S/C28H29ClN4O2S2/c29-24-11-9-22(10-12-24)26(34)8-4-2-1-3-5-13-37-28-32-27(35)23(15-21-16-30-20-31-17-21)18-33(28)19-25-7-6-14-36-25/h6-7,9-12,14,16-18,20H,1-5,8,13,15,19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
					More data for this Ligand-Target Pair