BDBM50093928 2-[2-(4-Fluoro-benzylsulfanyl)-4-oxo-5-pyrimidin-5-ylmethyl-4H-pyrimidin-1-yl]-N-[6-(4-fluoro-phenyl)-hexyl]-acetamide::CHEMBL83522

SMILES: Fc1ccc(CCCCCCNC(=O)Cn2cc(Cc3cncnc3)c(=O)nc2SCc2ccc(F)cc2)cc1

InChI Key: InChIKey=AZJVECSUDNMZJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093928 (2-[2-(4-Fluoro-benzylsulfanyl)-4-oxo-5-pyrimidin-5...) Show SMILES Fc1ccc(CCCCCCNC(=O)Cn2cc(Cc3cncnc3)c(=O)nc2SCc2ccc(F)cc2)cc1 Show InChI InChI=1S/C30H31F2N5O2S/c31-26-10-6-22(7-11-26)5-3-1-2-4-14-35-28(38)19-37-18-25(15-24-16-33-21-34-17-24)29(39)36-30(37)40-20-23-8-12-27(32)13-9-23/h6-13,16-18,21H,1-5,14-15,19-20H2,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
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