BDBM50093995 2-(2-Carboxymethoxy-cyclohexylmethyl)-4-(6-chloro-benzo[1,3]dioxol-5-ylmethyl)-5-phenyl-2H-pyrazole-3-carboxylic acid::CHEMBL314973
SMILES: OC(=O)COC1CCCCC1Cn1nc(c(Cc2cc3OCOc3cc2Cl)c1C(O)=O)-c1ccccc1
InChI Key: InChIKey=HDYKWOBJYYWUAM-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EDNRA (RAT) | BDBM50093995 (2-(2-Carboxymethoxy-cyclohexylmethyl)-4-(6-chloro-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst Marion Roussel Curated by ChEMBL | Assay Description In vitro binding affinity to endothelin A receptor in rat heart ventricles | Bioorg Med Chem Lett 10: 2575-8 (2001) BindingDB Entry DOI: 10.7270/Q22R3QW9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
EDNRB (RAT) | BDBM50093995 (2-(2-Carboxymethoxy-cyclohexylmethyl)-4-(6-chloro-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst Marion Roussel Curated by ChEMBL | Assay Description In vitro binding affinity to endothelin B receptor in rat cerebellum | Bioorg Med Chem Lett 10: 2575-8 (2001) BindingDB Entry DOI: 10.7270/Q22R3QW9 | |||||||||||
More data for this Ligand-Target Pair |