BDBM50094114 2-(6-Carbamimidoyl-benzoimidazol-1-yl)-N-(2'-sulfamoyl-biphenyl-4-yl)-acetamide::CHEMBL343495

SMILES: NC(=N)c1ccc2ncn(CC(=O)Nc3ccc(cc3)-c3ccccc3S(N)(=O)=O)c2c1

InChI Key: InChIKey=MPKMAEAWPAAGEP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50094114 (2-(6-Carbamimidoyl-benzoimidazol-1-yl)-N-(2'-sulfa...) Show SMILES NC(=N)c1ccc2ncn(CC(=O)Nc3ccc(cc3)-c3ccccc3S(N)(=O)=O)c2c1 Show InChI InChI=1S/C22H20N6O3S/c23-22(24)15-7-10-18-19(11-15)28(13-26-18)12-21(29)27-16-8-5-14(6-9-16)17-3-1-2-4-20(17)32(25,30)31/h1-11,13H,12H2,(H3,23,24)(H,27,29)(H2,25,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 43: 4398-415 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PP5
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50094114 (2-(6-Carbamimidoyl-benzoimidazol-1-yl)-N-(2'-sulfa...) Show SMILES NC(=N)c1ccc2ncn(CC(=O)Nc3ccc(cc3)-c3ccccc3S(N)(=O)=O)c2c1 Show InChI InChI=1S/C22H20N6O3S/c23-22(24)15-7-10-18-19(11-15)28(13-26-18)12-21(29)27-16-8-5-14(6-9-16)17-3-1-2-4-20(17)32(25,30)31/h1-11,13H,12H2,(H3,23,24)(H,27,29)(H2,25,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human trypsin				J Med Chem 43: 4398-415 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50094114 (2-(6-Carbamimidoyl-benzoimidazol-1-yl)-N-(2'-sulfa...) Show SMILES NC(=N)c1ccc2ncn(CC(=O)Nc3ccc(cc3)-c3ccccc3S(N)(=O)=O)c2c1 Show InChI InChI=1S/C22H20N6O3S/c23-22(24)15-7-10-18-19(11-15)28(13-26-18)12-21(29)27-16-8-5-14(6-9-16)17-3-1-2-4-20(17)32(25,30)31/h1-11,13H,12H2,(H3,23,24)(H,27,29)(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human thrombin				J Med Chem 43: 4398-415 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PP5
					More data for this Ligand-Target Pair