BDBM50094324 3-Pentafluorobenzenesulfonylamino-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide::CHEMBL138920

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)s1

InChI Key: InChIKey=XMOVBRJIOBDWGP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50094324 (3-Pentafluorobenzenesulfonylamino-N-(5-sulfamoyl-[...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)s1 Show InChI InChI=1S/C11H8F5N5O5S3/c12-4-5(13)7(15)9(8(16)6(4)14)29(25,26)18-2-1-3(22)19-10-20-21-11(27-10)28(17,23)24/h18H,1-2H2,(H2,17,23,24)(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase II (CA2)				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50094324 (3-Pentafluorobenzenesulfonylamino-N-(5-sulfamoyl-[...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)s1 Show InChI InChI=1S/C11H8F5N5O5S3/c12-4-5(13)7(15)9(8(16)6(4)14)29(25,26)18-2-1-3(22)19-10-20-21-11(27-10)28(17,23)24/h18H,1-2H2,(H2,17,23,24)(H,19,20,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of bovine carbonic anhydrase IV (CA4) from bovine lung microsomes				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50094324 (3-Pentafluorobenzenesulfonylamino-N-(5-sulfamoyl-[...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)s1 Show InChI InChI=1S/C11H8F5N5O5S3/c12-4-5(13)7(15)9(8(16)6(4)14)29(25,26)18-2-1-3(22)19-10-20-21-11(27-10)28(17,23)24/h18H,1-2H2,(H2,17,23,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase I (CA1)				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair