BDBM50094393 4-Methyl-5-pentafluorobenzenesulfonylimino-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide::CHEMBL138253

SMILES: Cn1nc(sc1=NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)S(N)(=O)=O

InChI Key: InChIKey=FVMJBLJQHQYJPU-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50094393 (4-Methyl-5-pentafluorobenzenesulfonylimino-4,5-dih...) Show SMILES Cn1nc(sc1=NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)S(N)(=O)=O Show InChI InChI=1S/C9H5F5N4O4S3/c1-18-8(23-9(16-18)24(15,19)20)17-25(21,22)7-5(13)3(11)2(10)4(12)6(7)14/h1H3,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase II (CA2)				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50094393 (4-Methyl-5-pentafluorobenzenesulfonylimino-4,5-dih...) Show SMILES Cn1nc(sc1=NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)S(N)(=O)=O Show InChI InChI=1S/C9H5F5N4O4S3/c1-18-8(23-9(16-18)24(15,19)20)17-25(21,22)7-5(13)3(11)2(10)4(12)6(7)14/h1H3,(H2,15,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of bovine carbonic anhydrase IV (CA4) from bovine lung microsomes				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50094393 (4-Methyl-5-pentafluorobenzenesulfonylimino-4,5-dih...) Show SMILES Cn1nc(sc1=NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)S(N)(=O)=O Show InChI InChI=1S/C9H5F5N4O4S3/c1-18-8(23-9(16-18)24(15,19)20)17-25(21,22)7-5(13)3(11)2(10)4(12)6(7)14/h1H3,(H2,15,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase I (CA1)				J Med Chem 43: 4542-51 (2000) BindingDB Entry DOI: 10.7270/Q2BV7HBP
					More data for this Ligand-Target Pair