BDBM50094884 CHEMBL3589154

SMILES: COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=GRPZZKMUWKOODM-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50094884 (CHEMBL3589154) Show SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN2O4S/c1-23(2,28)12-30-18-9-8-16(10-19(18)29-3)26-13-25-17-11-20(31-21(17)22(26)27)14-4-6-15(24)7-5-14/h4-11,13,28H,12H2,1-3H3	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysis				Bioorg Med Chem Lett 25: 4412-8 (2015) BindingDB Entry DOI: 10.7270/Q2JD4ZMW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50094884 (CHEMBL3589154) Show SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN2O4S/c1-23(2,28)12-30-18-9-8-16(10-19(18)29-3)26-13-25-17-11-20(31-21(17)22(26)27)14-4-6-15(24)7-5-14/h4-11,13,28H,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-induced Ca2+ influx for 120 mins by FLIPR assay				Bioorg Med Chem Lett 25: 4412-8 (2015) BindingDB Entry DOI: 10.7270/Q2JD4ZMW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50094884 (CHEMBL3589154) Show SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN2O4S/c1-23(2,28)12-30-18-9-8-16(10-19(18)29-3)26-13-25-17-11-20(31-21(17)22(26)27)14-4-6-15(24)7-5-14/h4-11,13,28H,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...				Bioorg Med Chem Lett 25: 2793-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053
					More data for this Ligand-Target Pair