BDBM50095039 CHEMBL328459::Ethyl-{2-[2-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amine

SMILES: CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1

InChI Key: InChIKey=GILFIXAIAPMQCS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50095039 (CHEMBL328459 | Ethyl-{2-[2-(4-fluoro-phenyl)-1H-in...) Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN2/c1-3-22(2)13-12-17-16-6-4-5-7-18(16)21-19(17)14-8-10-15(20)11-9-14/h4-11,21H,3,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacent of [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 10: 2697-9 (2000) BindingDB Entry DOI: 10.7270/Q27943XR
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50095039 (CHEMBL328459 | Ethyl-{2-[2-(4-fluoro-phenyl)-1H-in...) Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN2/c1-3-22(2)13-12-17-16-6-4-5-7-18(16)21-19(17)14-8-10-15(20)11-9-14/h4-11,21H,3,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from CHO cells expressing human Dopamine receptor D2.				Bioorg Med Chem Lett 10: 2697-9 (2000) BindingDB Entry DOI: 10.7270/Q27943XR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50095039 (CHEMBL328459 | Ethyl-{2-[2-(4-fluoro-phenyl)-1H-in...) Show SMILES CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN2/c1-3-22(2)13-12-17-16-6-4-5-7-18(16)21-19(17)14-8-10-15(20)11-9-14/h4-11,21H,3,12-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [H]-mesulergine from CHO cells expressing human 5-hydroxytryptamine 2C receptor.				Bioorg Med Chem Lett 10: 2697-9 (2000) BindingDB Entry DOI: 10.7270/Q27943XR
					More data for this Ligand-Target Pair