BDBM50095342 2-(2,4-Dichloro-phenyl)-3,5,7-trihydroxy-chromen-4-one::CHEMBL165607

SMILES: Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=SKWMTRHMWQXILY-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50095342 (2-(2,4-Dichloro-phenyl)-3,5,7-trihydroxy-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2O5/c16-6-1-2-8(9(17)3-6)15-14(21)13(20)12-10(19)4-7(18)5-11(12)22-15/h1-5,18-19,21H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Binding affinity to ABCB1 nucleotide binding domain 2				Eur J Med Chem 46: 4078-88 (2011) Article DOI: 10.1016/j.ejmech.2011.06.008 BindingDB Entry DOI: 10.7270/Q2FJ2J3W
					More data for this Ligand-Target Pair
P-glycoprotein (P-gp) (Mus musculus (Mouse))	BDBM50095342 (2-(2,4-Dichloro-phenyl)-3,5,7-trihydroxy-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2O5/c16-6-1-2-8(9(17)3-6)15-14(21)13(20)12-10(19)4-7(18)5-11(12)22-15/h1-5,18-19,21H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair