BDBM50095619 CHEMBL147950::[3-(3,4-Dichloro-phenyl)-indan-1-yl]-ethyl-amine;chloride
SMILES: CN(C)[C@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=UNCBFTIAWJTNTF-YOEHRIQHSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI. | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair |