BDBM50095677 2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-ylmethyl-piperidin-4-yl)-acetamide::CHEMBL358193

SMILES: OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1

InChI Key: InChIKey=DUJZVZNVMYQVAM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095677 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c26-22(23(27,20-8-4-5-9-20)19-6-2-1-3-7-19)24-21-10-13-25(14-11-21)16-18-12-15-28-17-18/h1-3,6-7,12,15,17,20-21,27H,4-5,8-11,13-14,16H2,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095677 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c26-22(23(27,20-8-4-5-9-20)19-6-2-1-3-7-19)24-21-10-13-25(14-11-21)16-18-12-15-28-17-18/h1-3,6-7,12,15,17,20-21,27H,4-5,8-11,13-14,16H2,(H,24,26)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50095677 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c26-22(23(27,20-8-4-5-9-20)19-6-2-1-3-7-19)24-21-10-13-25(14-11-21)16-18-12-15-28-17-18/h1-3,6-7,12,15,17,20-21,27H,4-5,8-11,13-14,16H2,(H,24,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M2 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair