BDBM50095798 CHEMBL3590498

SMILES: [O-]S(=O)(=O)C(F)(F)F.Cc1ccc(cc1)-c1ccc(cc1)C#Cc1cccc(C#Cc2ccc(cc2)-c2ccc(C)cc2)[n+]1C

InChI Key: InChIKey=DHSPIKQYPLRMDQ-UHFFFAOYSA-M

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095798 (CHEMBL3590498) Show SMILES [O-]S(=O)(=O)C(F)(F)F.Cc1ccc(cc1)-c1ccc(cc1)C#Cc1cccc(C#Cc2ccc(cc2)-c2ccc(C)cc2)[n+]1C Show InChI InChI=1S/C36H28N.CHF3O3S/c1-27-7-17-31(18-8-27)33-21-11-29(12-22-33)15-25-35-5-4-6-36(37(35)3)26-16-30-13-23-34(24-14-30)32-19-9-28(2)10-20-32;2-1(3,4)8(5,6)7/h4-14,17-24H,1-3H3;(H,5,6,7)/q+1;/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	303	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human Kv11.1 expressed in HEK293 cell membranes by competitive radioligand displacement assay				J Med Chem 58: 5916-29 (2015) Article DOI: 10.1021/acs.jmedchem.5b00518 BindingDB Entry DOI: 10.7270/Q2FX7C6V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095798 (CHEMBL3590498) Show SMILES [O-]S(=O)(=O)C(F)(F)F.Cc1ccc(cc1)-c1ccc(cc1)C#Cc1cccc(C#Cc2ccc(cc2)-c2ccc(C)cc2)[n+]1C Show InChI InChI=1S/C36H28N.CHF3O3S/c1-27-7-17-31(18-8-27)33-21-11-29(12-22-33)15-25-35-5-4-6-36(37(35)3)26-16-30-13-23-34(24-14-30)32-19-9-28(2)10-20-32;2-1(3,4)8(5,6)7/h4-14,17-24H,1-3H3;(H,5,6,7)/q+1;/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Binding affinity to human Kv11.1 expressed in HEK293 cell membranes assessed as binding affinity constant by [3H]dofetilide competition association a...				J Med Chem 58: 5916-29 (2015) Article DOI: 10.1021/acs.jmedchem.5b00518 BindingDB Entry DOI: 10.7270/Q2FX7C6V
					More data for this Ligand-Target Pair