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SMILES: Oc1ccc2cc(-c3nc(cs3)-c3ccc4OCOc4c3)c(=O)oc2c1

InChI Key: InChIKey=ZMLKTTGOZOAAOW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096002   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage migration inhibitory factor


(Homo sapiens (Human))		BDBM50096002
PNG
(3-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-7-hydroxy...)
Show SMILES Oc1ccc2cc(-c3nc(cs3)-c3ccc4OCOc4c3)c(=O)oc2c1
Show InChI InChI=1S/C19H11NO5S/c21-12-3-1-11-5-13(19(22)25-16(11)7-12)18-20-14(8-26-18)10-2-4-15-17(6-10)24-9-23-15/h1-8,21H,9H2
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem

Patents
PubMed
 1.50E+3n/an/an/an/an/an/an/an/a



Yamanouchi Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)

J Med Chem 44: 540-7 (2001)


BindingDB Entry DOI: 10.7270/Q2W66MGR
More data for this
Ligand-Target Pair