BDBM50096106 2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid methyl-(2'-sulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL358834

SMILES: CN(C(=O)c1cc(C)nn1-c1cccc(c1)C(N)=N)c1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=YPDIBIQZTIWETC-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50096106 (2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...) Show SMILES CN(C(=O)c1cc(C)nn1-c1cccc(c1)C(N)=N)c1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C25H24N6O3S/c1-16-14-22(31(29-16)20-7-5-6-18(15-20)24(26)27)25(32)30(2)19-12-10-17(11-13-19)21-8-3-4-9-23(21)35(28,33)34/h3-15H,1-2H3,(H3,26,27)(H2,28,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 566-78 (2001) BindingDB Entry DOI: 10.7270/Q2RF5VQK
					More data for this Ligand-Target Pair
Trypsin II (Homo sapiens (Human))	BDBM50096106 (2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...) Show SMILES CN(C(=O)c1cc(C)nn1-c1cccc(c1)C(N)=N)c1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C25H24N6O3S/c1-16-14-22(31(29-16)20-7-5-6-18(15-20)24(26)27)25(32)30(2)19-12-10-17(11-13-19)21-8-3-4-9-23(21)35(28,33)34/h3-15H,1-2H3,(H3,26,27)(H2,28,33,34)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description In vitro activity against human trypsin.				J Med Chem 44: 566-78 (2001) BindingDB Entry DOI: 10.7270/Q2RF5VQK
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50096106 (2-(3-Carbamimidoyl-phenyl)-5-methyl-2H-pyrazole-3-...) Show SMILES CN(C(=O)c1cc(C)nn1-c1cccc(c1)C(N)=N)c1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C25H24N6O3S/c1-16-14-22(31(29-16)20-7-5-6-18(15-20)24(26)27)25(32)30(2)19-12-10-17(11-13-19)21-8-3-4-9-23(21)35(28,33)34/h3-15H,1-2H3,(H3,26,27)(H2,28,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description In vitro activity against human thrombin.				J Med Chem 44: 566-78 (2001) BindingDB Entry DOI: 10.7270/Q2RF5VQK
					More data for this Ligand-Target Pair