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SMILES: COc1c(Cl)ccc2NC(=O)NC(C#CC3CC3)(c12)C(F)(F)F

InChI Key: InChIKey=OQFZGAUGFPRBFJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096417   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50096417
PNG
(6-Chloro-4-cyclopropylethynyl-5-methoxy-4-trifluor...)
Show SMILES COc1c(Cl)ccc2NC(=O)NC(C#CC3CC3)(c12)C(F)(F)F
Show InChI InChI=1S/C15H12ClF3N2O2/c1-23-12-9(16)4-5-10-11(12)14(15(17,18)19,21-13(22)20-10)7-6-8-2-3-8/h4-5,8H,2-3H2,1H3,(H2,20,21,22)
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PubMed
n/an/a 70n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase

Bioorg Med Chem Lett 11: 211-4 (2001)


BindingDB Entry DOI: 10.7270/Q2319WDF
More data for this
Ligand-Target Pair