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SMILES: COc1c(Cl)ccc2NC(=O)NC(C#Cc3cccnc3)(c12)C(F)(F)F

InChI Key: InChIKey=XTIAUMZEWTUMKX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096421   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50096421
PNG
(6-Chloro-5-methoxy-4-pyridin-3-ylethynyl-4-trifluo...)
Show SMILES COc1c(Cl)ccc2NC(=O)NC(C#Cc3cccnc3)(c12)C(F)(F)F
Show InChI InChI=1S/C17H11ClF3N3O2/c1-26-14-11(18)4-5-12-13(14)16(17(19,20)21,24-15(25)23-12)7-6-10-3-2-8-22-9-10/h2-5,8-9H,1H3,(H2,23,24,25)
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MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 139n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase

Bioorg Med Chem Lett 11: 211-4 (2001)


BindingDB Entry DOI: 10.7270/Q2319WDF
More data for this
Ligand-Target Pair