BDBM50096459 1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-carboxylic acid 3,5-dichloro-benzylamide::CHEMBL75544

SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(Cl)cc(Cl)c2)c1

InChI Key: InChIKey=FCFGTZIDSYBJHD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50096459 (1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-c...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(Cl)cc(Cl)c2)c1 Show InChI InChI=1S/C24H20Cl2N4O2/c25-17-8-15(9-18(26)10-17)12-29-24(32)21-11-19-20(5-2-6-22(19)31)30(21)13-14-3-1-4-16(7-14)23(27)28/h1-11,31H,12-13H2,(H3,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Curated by ChEMBL					Assay Description Inhibitory activity against serine protease factor Xa (fXa) was determined				Bioorg Med Chem Lett 11: 227-30 (2001) BindingDB Entry DOI: 10.7270/Q2KD1X68
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50096459 (1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-c...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(Cl)cc(Cl)c2)c1 Show InChI InChI=1S/C24H20Cl2N4O2/c25-17-8-15(9-18(26)10-17)12-29-24(32)21-11-19-20(5-2-6-22(19)31)30(21)13-14-3-1-4-16(7-14)23(27)28/h1-11,31H,12-13H2,(H3,27,28)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	771	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Curated by ChEMBL					Assay Description Inhibitory activity against thrombin was determined				Bioorg Med Chem Lett 11: 227-30 (2001) BindingDB Entry DOI: 10.7270/Q2KD1X68
					More data for this Ligand-Target Pair