BDBM50096632 CHEMBL3577274
SMILES: NC(=O)Cn1c2C[C@@H](CCc2c2cc(Cl)ccc12)C(O)=O
InChI Key: InChIKey=WEITVQPGVPEPAZ-MRVPVSSYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase III subunit beta (Escherichia coli (strain K12)) | BDBM50096632 (CHEMBL3577274) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Wollongong and The Illawarra Health and Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay | J Med Chem 58: 4693-702 (2015) Article DOI: 10.1021/acs.jmedchem.5b00232 BindingDB Entry DOI: 10.7270/Q2KK9DJ9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA polymerase III subunit beta (Escherichia coli (strain K12)) | BDBM50096632 (CHEMBL3577274) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Wollongong and The Illawarra Health and Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay | J Med Chem 58: 4693-702 (2015) Article DOI: 10.1021/acs.jmedchem.5b00232 BindingDB Entry DOI: 10.7270/Q2KK9DJ9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |