null

SMILES: ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=QYMKPTMAFMKKTC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50096653 (2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...) Show SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H24N2O5/c29-24(27-32)20(9-6-16-28-25(30)22-10-4-5-11-23(22)26(28)31)17-33-21-14-12-19(13-15-21)18-7-2-1-3-8-18/h1-5,7-8,10-15,20,32H,6,9,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-9				Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50096653 (2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...) Show SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H24N2O5/c29-24(27-32)20(9-6-16-28-25(30)22-10-4-5-11-23(22)26(28)31)17-33-21-14-12-19(13-15-21)18-7-2-1-3-8-18/h1-5,7-8,10-15,20,32H,6,9,16-17H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-13				Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50096653 (2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...) Show SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H24N2O5/c29-24(27-32)20(9-6-16-28-25(30)22-10-4-5-11-23(22)26(28)31)17-33-21-14-12-19(13-15-21)18-7-2-1-3-8-18/h1-5,7-8,10-15,20,32H,6,9,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	313	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-3				Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50096653 (2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...) Show SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H24N2O5/c29-24(27-32)20(9-6-16-28-25(30)22-10-4-5-11-23(22)26(28)31)17-33-21-14-12-19(13-15-21)18-7-2-1-3-8-18/h1-5,7-8,10-15,20,32H,6,9,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-1				Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50096653 (2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...) Show SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H24N2O5/c29-24(27-32)20(9-6-16-28-25(30)22-10-4-5-11-23(22)26(28)31)17-33-21-14-12-19(13-15-21)18-7-2-1-3-8-18/h1-5,7-8,10-15,20,32H,6,9,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-2				Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9
					More data for this Ligand-Target Pair