null
SMILES: CCCCCCCCCCCCCCCCC(=O)NCC(=O)Nc1cccc(c1)S(=O)(=O)Nc1cccc(C)c1C
InChI Key: InChIKey=CYSRBNOFNVFPLU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50096861 (CHEMBL440905 | Heptadecanoic acid {[3-(2,3-dimethy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universität Marburg Curated by ChEMBL | Assay Description Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uM | Bioorg Med Chem Lett 11: 425-7 (2001) BindingDB Entry DOI: 10.7270/Q20G3JF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50096861 (CHEMBL440905 | Heptadecanoic acid {[3-(2,3-dimethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universität Marburg Curated by ChEMBL | Assay Description Inhibitory activity against Farnesyltransferase | Bioorg Med Chem Lett 11: 425-7 (2001) BindingDB Entry DOI: 10.7270/Q20G3JF1 | |||||||||||
More data for this Ligand-Target Pair |