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SMILES: [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccc(F)cc2NC(=O)C1

InChI Key: InChIKey=HAYZVQTVIDVNHD-KSSFIOAISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096868   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50096868
PNG
(CHEMBL3580779)
Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccc(F)cc2NC(=O)C1 |r|
Show InChI InChI=1S/C21H20F3N3O2/c22-13-3-1-12-9-27(10-20(28)26-19(12)6-13)21(29)8-18(25)14-4-2-11-5-16(23)17(24)7-15(11)14/h1,3,5-7,14,18H,2,4,8-10,25H2,(H,26,28)/t14-,18-/m0/s1
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Similars
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of DPP4 extracted from human Caco2 cells using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay

ACS Med Chem Lett 6: 602-6 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00074
BindingDB Entry DOI: 10.7270/Q22J6DM2
More data for this
Ligand-Target Pair