null

SMILES: [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key: InChIKey=XTAFGJNJWKVLFD-HZMBPMFUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50096874 (CHEMBL3580775) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F |r| Show InChI InChI=1S/C18H18F5N5O/c19-12-5-9-1-2-10(11(9)6-13(12)20)14(24)7-16(29)27-3-4-28-15(8-27)25-26-17(28)18(21,22)23/h5-6,10,14H,1-4,7-8,24H2/t10-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DPP4 extracted from human Caco2 cells using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50096874 (CHEMBL3580775) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F |r| Show InChI InChI=1S/C18H18F5N5O/c19-12-5-9-1-2-10(11(9)6-13(12)20)14(24)7-16(29)27-3-4-28-15(8-27)25-26-17(28)18(21,22)23/h5-6,10,14H,1-4,7-8,24H2/t10-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human ERG channel				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50096874 (CHEMBL3580775) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F |r| Show InChI InChI=1S/C18H18F5N5O/c19-12-5-9-1-2-10(11(9)6-13(12)20)14(24)7-16(29)27-3-4-28-15(8-27)25-26-17(28)18(21,22)23/h5-6,10,14H,1-4,7-8,24H2/t10-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP9 using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50096874 (CHEMBL3580775) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F |r| Show InChI InChI=1S/C18H18F5N5O/c19-12-5-9-1-2-10(11(9)6-13(12)20)14(24)7-16(29)27-3-4-28-15(8-27)25-26-17(28)18(21,22)23/h5-6,10,14H,1-4,7-8,24H2/t10-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair