BDBM50096880 CHEMBL3580788

SMILES: [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(C)C(=O)C1

InChI Key: InChIKey=XXSRKEYKCVAYLV-KXBFYZLASA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50096880 (CHEMBL3580788) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(C)C(=O)C1 |r| Show InChI InChI=1S/C22H23F2N3O2/c1-26-20-5-3-2-4-14(20)11-27(12-22(26)29)21(28)10-19(25)15-7-6-13-8-17(23)18(24)9-16(13)15/h2-5,8-9,15,19H,6-7,10-12,25H2,1H3/t15-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DPP4 extracted from human Caco2 cells using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50096880 (CHEMBL3580788) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(C)C(=O)C1 |r| Show InChI InChI=1S/C22H23F2N3O2/c1-26-20-5-3-2-4-14(20)11-27(12-22(26)29)21(28)10-19(25)15-7-6-13-8-17(23)18(24)9-16(13)15/h2-5,8-9,15,19H,6-7,10-12,25H2,1H3/t15-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP9 using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50096880 (CHEMBL3580788) Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(C)C(=O)C1 |r| Show InChI InChI=1S/C22H23F2N3O2/c1-26-20-5-3-2-4-14(20)11-27(12-22(26)29)21(28)10-19(25)15-7-6-13-8-17(23)18(24)9-16(13)15/h2-5,8-9,15,19H,6-7,10-12,25H2,1H3/t15-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay				ACS Med Chem Lett 6: 602-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00074 BindingDB Entry DOI: 10.7270/Q22J6DM2
					More data for this Ligand-Target Pair