null
SMILES: S=C(NCC12CC3CC(CC(C3)C1)C2)Nc1nccs1
InChI Key: InChIKey=YVDWMGNODCFVJL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50097038 (1-Adamantan-1-ylmethyl-3-thiazol-2-yl-thiourea | C...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Compound was tested for agonistic activity against 5-HT uptake | Bioorg Med Chem Lett 11: 523-8 (2001) BindingDB Entry DOI: 10.7270/Q237780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50097038 (1-Adamantan-1-ylmethyl-3-thiazol-2-yl-thiourea | C...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ... | Bioorg Med Chem Lett 11: 523-8 (2001) BindingDB Entry DOI: 10.7270/Q237780X | |||||||||||
More data for this Ligand-Target Pair |