BDBM50097226 4-Benzhydrylidene-1-methyl-piperidine::CHEMBL347536
SMILES: [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccccc1
InChI Key: InChIKey=PPACNRLZTRXGPJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50097226 (4-Benzhydrylidene-1-methyl-piperidine | CHEMBL3475...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor from rat forebrain using [3H]-ketanserin as radioligand | Bioorg Med Chem Lett 11: 563-6 (2001) BindingDB Entry DOI: 10.7270/Q29S1Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SET domain-containing protein 7/9 (Set7/9) (Homo sapiens (Human)) | BDBM50097226 (4-Benzhydrylidene-1-methyl-piperidine | CHEMBL3475...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University (TMDU) Curated by ChEMBL | Assay Description Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assay | Bioorg Med Chem 24: 4318-4323 (2016) BindingDB Entry DOI: 10.7270/Q2959KGV | |||||||||||
More data for this Ligand-Target Pair |