BDBM50097491 CHEMBL3585876

SMILES: CC1CN(CC(C)O1)C(=O)CCO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1

InChI Key: InChIKey=XPOFGDHMYRXQEG-BRJLIKDPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50097491 (CHEMBL3585876) Show SMILES CC1CN(CC(C)O1)C(=O)CCO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1 Show InChI InChI=1S/C22H30F2N2O5/c1-15-13-26(14-16(2)29-15)21(27)9-10-28-25-12-17-7-8-19(31-22(23)24)20(11-17)30-18-5-3-4-6-18/h7-8,11-12,15-16,18,22H,3-6,9-10,13-14H2,1-2H3/b25-12+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay				Bioorg Med Chem 23: 3426-35 (2015) Article DOI: 10.1016/j.bmc.2015.04.027 BindingDB Entry DOI: 10.7270/Q2NC62ZZ
					More data for this Ligand-Target Pair