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SMILES: FC(F)(F)c1cc(Br)cc(NC(=O)Nc2ccc(cc2)-c2cccnc2)c1

InChI Key: InChIKey=RZJVXSBEHJHQTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097508   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50097508
PNG
(CHEMBL3586049)
Show SMILES FC(F)(F)c1cc(Br)cc(NC(=O)Nc2ccc(cc2)-c2cccnc2)c1
Show InChI InChI=1S/C19H13BrF3N3O/c20-15-8-14(19(21,22)23)9-17(10-15)26-18(27)25-16-5-3-12(4-6-16)13-2-1-7-24-11-13/h1-11H,(H2,25,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.360n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 (unknown origin) after 1 hr by ADP-Glo assay

Bioorg Med Chem 23: 3228-36 (2015)


Article DOI: 10.1016/j.bmc.2015.04.071
BindingDB Entry DOI: 10.7270/Q2CV4KGG
More data for this
Ligand-Target Pair